Thalamic neuromodulation and its implications for executive networks
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Thalamic neuromodulation and its implications for executive networks
The thalamus is a key structure that controls the routing of information in the brain. Understanding modulation at the thalamic level is critical to understanding the flow of information to brain regions involved in cognitive functions, such as the neocortex, the hippocampus, and the basal ganglia. Modulators contribute the majority of synapses that thalamic cells receive, and the highest fract...
متن کاملPrefrontal-Thalamic Anatomical Connectivity and Executive Cognitive Function in Schizophrenia.
BACKGROUND Executive cognitive functions, including working memory, cognitive flexibility, and inhibition, are impaired in schizophrenia. Executive functions rely on coordinated information processing between the prefrontal cortex (PFC) and thalamus, particularly the mediodorsal nucleus. This raises the possibility that anatomical connectivity between the PFC and mediodorsal thalamus may be 1) ...
متن کاملCommunication skills and thalamic lesion: Strategies of rehabilitation.
AIM To describe the speech rehabilitation history of patients with thalamic lesions. BACKGROUND Thalamic lesions can affect speech and language according to diverse thalamic nuclei involved. Because of the strategic functional position of the thalamus within the cognitive networks, its lesion can also interfere with other cognitive processes, such as attention, memory and executive functions....
متن کاملEditorial: Neuromodulation of executive circuits
The executive control of behavior involves functional interactions between the frontal cortex and other cortical and subcortical brain regions, in particular with the striatum and thalamus, via parallel fronto-striatal-thalamic loops. In all of these brain regions, neuronal excitability, and synaptic transmission are regulated by serotonergic, dopaminergic, cholinergic, adrenergic, and peptider...
متن کاملImmediate effects of deep brain stimulation of anterior thalamic nuclei on executive functions and emotion-attention interaction in humans
BACKGROUND Deep brain stimulation (DBS) of anterior thalamic nuclei (ANT) is a novel promising therapeutic method for treating refractory epilepsy. Despite reports of subjective memory impairments and mood disturbances in patients with ANT-DBS, little is known of its effects on cognitive and affective processes. HYPOTHESIS The anterior thalamus has connections to prefrontal and limbic network...
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تاریخ انتشار 2014